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The Alpha Omega City-Wide Chapter of Delta Sigma Theta Sorority, Incorporated is located in the St. Louis Metropolitan area and serves the following nine colleges/universities:​​
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Fontbonne University
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Harris Stowe State University
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Lindenwood University
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Maryville University
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Saint Louis University
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University of Health Sciences and Pharmacy
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University of Missouri-St. Louis
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Washington University in St. Louis
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Webster University
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